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The Best Road Trip Routes Across North America

By Anita Singh
USA Lifestyle 4 min read| 01 Oct 2025

North America is a dream destination for road trippers, offering an incredible variety of landscapes, cities, and scenic routes. Whether you're driving through the sweeping deserts of the American Southwest or exploring the rugged coastlines of Canada, the continent is filled with iconic routes that offer unforgettable experiences. Here are some of the best road trip routes across North America that should be on every traveler’s bucket list.

ImageRoute 66: The Mother Road

One of the most famous road trips in North America, Route 66 spans from Chicago to Santa Monica, California, covering over 2,000 miles of history, culture, and diverse landscapes. Known as the “Mother Road,” this iconic highway takes you through small towns, vibrant cities, and a mix of classic Americana landmarks.

Along the way, you can explore quirky roadside attractions, visit historic Route 66 diners, and experience the charm of towns that have preserved their retro vibes. Don’t forget to stop at the Grand Canyon, Petrified Forest National Park, and Cadillac Ranch, among other must-see sights.

Pacific Coast Highway (California)

The Pacific Coast Highway, also known as California State Route 1, is a stunning route that hugs the coastline of California from San Diego to San Francisco. This scenic drive offers breathtaking views of the Pacific Ocean, rugged cliffs, and beautiful beaches, making it one of the most picturesque road trips in the world.

Highlights of the Pacific Coast Highway include the famous Bixby Creek Bridge, the charming town of Carmel-by-the-Sea, and the dramatic cliffs of Big Sur. You’ll also pass through iconic cities like Los Angeles and San Francisco, each offering a unique cultural experience.

The Cabot Trail (Canada)

For those looking to explore the stunning natural beauty of the Canadian Maritimes, the Cabot Trail in Nova Scotia is an absolute must. This 185-mile loop takes you through Cape Breton Highlands National Park, offering panoramic views of the Atlantic Ocean, towering cliffs, and pristine forests.

Along the way, you can stop at picturesque fishing villages, experience the vibrant Celtic culture of the region, and enjoy outdoor activities like hiking and whale watching. The Cabot Trail is particularly beautiful in the fall when the foliage is at its peak.

ImageThe Blue Ridge Parkway (Virginia & North Carolina)

Often referred to as “America’s Favorite Drive,” the Blue Ridge Parkway is a scenic highway that stretches through the Appalachian Mountains, connecting the Great Smoky Mountains National Park in North Carolina to Shenandoah National Park in Virginia.

This 469-mile route is known for its spectacular mountain views, waterfalls, and diverse wildlife. The Blue Ridge Parkway is particularly popular during the autumn months when the foliage transforms into vibrant shades of red, orange, and yellow. It’s a great place for hiking, camping, and photography.

The Alcan Highway (Alaska to Canada)

For an adventurous road trip that takes you deep into the wilderness, the Alaska-Canada Highway (also known as the Alcan Highway) is an epic route that stretches from Dawson Creek, British Columbia, to Fairbanks, Alaska.

The drive offers awe-inspiring views of glaciers, rivers, and dense forests, and you'll pass through remote towns and small communities. It’s a great route for those seeking solitude and natural beauty, and you may even encounter wildlife like moose, bison, and bears along the way.

The Great River Road (Mississippi River)

The Great River Road follows the winding path of the Mississippi River from Minnesota to Louisiana, offering a scenic and historic journey through the heart of America. The route takes you through charming river towns, past sprawling farmland, and into bustling cities like St. Louis, Memphis, and New Orleans.

Along the way, you can visit historic sites like Mark Twain’s childhood home in Hannibal, Missouri, or explore the vibrant music scene in Memphis. The Great River Road is also a perfect trip for those interested in exploring American history and culture.

The Icefields Parkway (Canada)

For road trippers looking to experience the dramatic beauty of the Canadian Rockies, the Icefields Parkway is a must-do route. This 143-mile highway connects Banff National Park to Jasper National Park in Alberta and is considered one of the most scenic drives in the world.

Along the route, you’ll encounter glaciers, turquoise lakes, towering mountains, and abundant wildlife. Stop to see the Athabasca Glacier, the Columbia Icefield, and the breathtaking Bow Lake, and be sure to take in the awe-inspiring views from every turn.

The Overseas Highway (Florida Keys)

For a road trip that combines stunning ocean views with tropical charm, the Overseas Highway in Florida is a perfect choice. This 113-mile route takes you from Miami to Key West, crossing a series of bridges that link the islands of the Florida Keys.

The drive offers incredible views of the turquoise waters of the Gulf of Mexico and the Atlantic Ocean. Along the way, you can stop at the colorful islands and enjoy activities like snorkeling, fishing, and exploring the unique culture of the Florida Keys.

Conclusion

No matter where you go, North America offers some of the best road trip routes in the world. Whether you prefer coastal views, mountain landscapes, or historic routes, these road trips provide the perfect opportunity to explore the diverse beauty and culture of the continent. So pack up the car, hit the open road, and create unforgettable memories on your next adventure.

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